Methods and compositions; purified preparation of neural progenitor regulatory factor

摘要

A novel substantially purified preparation of a neural progenitor regulatory factor and methods for producing such purified factor are claimed. In a preferred embodiment, the factor has an approximate molecular weight of about 46-47 kilodaltons (as determined by SDS polyacrylamide gel electrophoresis), has affinity for heparin, and stimulates proliferation of 0-2A glial progenitor cells.