| 发明名称 |
HETEROARYLNAPHTHALENES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS |
| 摘要 |
TITLE OF THE INVENTION HETEROARYLNAPHTHALENES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS Compounds having the formula I: <IMG> are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, antiallergic, anti-inflammatory, and cytoprotective agents. They are a1so useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
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| 申请公布号 |
CA2099061(A1) |
申请公布日期 |
1993.12.30 |
| 申请号 |
CA19932099061 |
申请日期 |
1993.06.23 |
| 申请人 |
MERCK FROSST CANADA INC. |
发明人 |
GIRARD, YVES;FORTIN, REJEAN;DELORME, DANIEL;DUBE, DANIEL;HAMEL, PIERRE;LEPINE, CAROLE;DUCHARME, YVES |
| 分类号 |
A61K31/35;A61K31/351;A61K31/38;A61K31/41;A61K31/425;A61K31/44;A61K31/443;A61K31/4433;A61K31/505;A61P9/08;A61P9/10;A61P11/00;A61P13/02;A61P15/00;A61P29/00;A61P37/08;A61P43/00;C07D309/10;C07D309/20;C07D405/04;C07D405/12;C07D405/14;C07D407/12;C07D409/12;C07D409/14;C07D417/04;C07D417/12;C07D417/14;C07D493/08;(IPC1-7):C07H7/04;C07H19/01;C07H15/04;C07D309/08;C07D497/12;A61K31/70 |
主分类号 |
A61K31/35 |
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