发明名称 SURFACE MODIFIED NSAID NANOPARTICLES
摘要 <p>Dispersible particles consisting essentially of a crystalline NSAID having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm. Pharmaceutical compositions containing the particles exhibit reduced gastric irritation following oral administration and/or hastened onset of action.</p>
申请公布号 WO1993025190(A1) 申请公布日期 1993.12.23
申请号 US1993005082 申请日期 1993.06.01
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