发明名称 |
CRYSTALLIZATION OF M-CSF |
摘要 |
The present invention is directed to methods for crystallizing macrophage colony stimulating factor. The present invention is also directed to methods for designing and producing M-CSF agonists and antagonists using information derived from the crystallographic structure of M-CSF. The invention is also directed to metho ds for screening M-CSF agonists and antagonists. In addition, the present invention is directed to an isolated, purified, solubl e and functional M-CSF receptor.
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申请公布号 |
CA2137793(A1) |
申请公布日期 |
1993.12.23 |
申请号 |
CA19932137793 |
申请日期 |
1993.06.09 |
申请人 |
CHIRON CORP;UNIV CALIFORNIA |
发明人 |
PANDIT JAYVARDHAN;JANCARIK JARMILA;KIM SUNG-HOU;KOTHS KIRSTON;HALENBECK ROBERT;FEAR ANNA L;TAYLOR ERIC;YAMAMOTO RALPH;BOHM ANDREW |
分类号 |
C12N15/02;A61K38/00;C07K14/53;C07K14/535;C07K14/715;C12N1/21;C12N15/09;C12N15/12;C12N15/27;C12P21/02;C12R1/19;G01N33/566;(IPC1-7):C12N15/27;C12Q1/02;C07K1/30;G01N33/68 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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