发明名称 CRYSTALLIZATION OF M-CSF
摘要 The present invention is directed to methods for crystallizing macrophage colony stimulating factor. The present invention is also directed to methods for designing and producing M-CSF agonists and antagonists using information derived from the crystallographic structure of M-CSF. The invention is also directed to metho ds for screening M-CSF agonists and antagonists. In addition, the present invention is directed to an isolated, purified, solubl e and functional M-CSF receptor.
申请公布号 CA2137793(A1) 申请公布日期 1993.12.23
申请号 CA19932137793 申请日期 1993.06.09
申请人 CHIRON CORP;UNIV CALIFORNIA 发明人 PANDIT JAYVARDHAN;JANCARIK JARMILA;KIM SUNG-HOU;KOTHS KIRSTON;HALENBECK ROBERT;FEAR ANNA L;TAYLOR ERIC;YAMAMOTO RALPH;BOHM ANDREW
分类号 C12N15/02;A61K38/00;C07K14/53;C07K14/535;C07K14/715;C12N1/21;C12N15/09;C12N15/12;C12N15/27;C12P21/02;C12R1/19;G01N33/566;(IPC1-7):C12N15/27;C12Q1/02;C07K1/30;G01N33/68 主分类号 C12N15/02
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