发明名称 Verfahren zur Darstellung eines reinen wasserloeslichen,therapeutische Eigenschaften aufweisenden Kondensationsproduktes von m-Kresolsulfonsaeure,mit Formaldehyd
摘要 A m-cresolsulphonic acid-formaldehyde condensation product is obtained by purifying an aqueous solution of m-cresolsulphonic acid containing sulphuric acid as impurity by adding a slight excess (with regard to the sulphuric acid) of barium carbonate or hydroxide, filtering off the precipitated barium sulphate, removing barium ions from the resulting solution by means of a cationic exchange resin and condensing the purified m-cresolsulphonic acid with formaldehyde, the molar ratio of m-cresolsulphonic acid to formaldehyde being from 3:1.125 to 3:1.85.ALSO:A m-cresolsulphonic acid-formaldehyde condensation product is obtained by purifying an aqueous solution of a m-cresolsulphonic acid (obtained in the form of a sulphonation product of m-cresol treated with sulphuric acid) by treating said solution with a slight excess (with regard to sulphuric acid) of barium carbonate or barium hydroxide, filtering off the barium sulphate, removing barium ions from the resulting solution by means of a cationic exchange resin, and then condensing the purified solution with formaldehyde, the molar ratio of m-cresolsulphonic acid to formaldehyde being from 3:1.125 to 3:1.85.ALSO:A therapeutic composition having astringent properties comprises a condensation product of m-cresolsulphonic acid with formaldehyde, the molar ratio of the acid to formaldehyde being from 3:1.125 to 3:1.85 and a suitable diluent, for example an aqueous solution thereof.
申请公布号 DE1518102(A1) 申请公布日期 1969.06.26
申请号 DE19651518102 申请日期 1965.03.09
申请人 PABIANICKIE ZAKLADY FARMACEUTYCZNE 发明人
分类号 A61K31/185;C07C309/43;C07G99/00;C08G8/18;C08L61/06 主分类号 A61K31/185
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