发明名称 Use of lipophilic muramyl peptide MDP:DD:GPD - in vaccines against HIV and tumours
摘要 Pharmaceutical compsn. contg. MDP-DD-GDP (I) are new., The compns. are pref. prepd. as vaccines contg. pathogenic agents, particularly human or mammnalian viruses or virus fractions. The prepn. of compsn. against HIV and tumours is esp. pref.. The compsns. are pref. biphasic, an aqueous phase and a hydrophobic phase. The hydrophobic phase may be a mineral oil, lipids, polyoxylene- polyoxypropylene polymers, polyoxyethylene sorbitan esters. USE - The compsns. exert a selective adjuvant action on the humoral or cellular mediation immunity response, or pref. both of these, without inducing auto-immune disorders. The action is similar to that of Freund's complete adjuvant, but without inducing the known side effects of this.
申请公布号 FR2692148(A1) 申请公布日期 1993.12.17
申请号 FR19920007126 申请日期 1992.06.12
申请人 VACSYN FRANCE SA 发明人 CHEDID LOUIS;AUDIBERT FRANCOISE;LEFRANCIER PIERRE
分类号 A61K38/14;A61K38/17;A61K39/39;(IPC1-7):A61K37/02 主分类号 A61K38/14
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