发明名称 Préparation et application de nouveaux systèmes colloïdaux nanovésiculaires dispersibles à base de cyclodextrine, sous forme de nanocapsules.
摘要 A nanovesicular system prepared by (1) preparing a liquid phase essentially consisting of a solution of cyclodextrin modified by acyl groups, and an oil in an organic solvent or solvent mixture; (2) preparing a second liquid phase essentially consisting of water or an aqueous mixture optionally containing one or more surfactants, one of said phases (1) and (2) optionally having an active molecule added thereto; and (3) gently stirring one of the liquid phases resulting from (1) or (2) into the other in order to obtain, almost instantaneously, a colloidal solution of modified cyclodextrin nanocapsules containing oil and optionally said active molecule. If required, all or part of the solvent or solvent mixture and all or part of the water or aqueous mixture may be removed. Said system may be used as a carrier for pharmaceuticals, cosmetics, chemicals, etc.
申请公布号 FR2692167(A1) 申请公布日期 1993.12.17
申请号 FR19920007285 申请日期 1992.06.16
申请人 CENTRE NAL RECHERC SCIENTIFIQUE 发明人 SKIBA MOHAMED;WOUESSIDJEWE DENIS;FESSI HATEM;DEVISSAGUET JEAN-PHILIPPE;DUCHENE DOMINIQUE;PUISIEUX FRANCIS
分类号 A61J3/07;A61K9/51;A61K47/40;A61K47/48;B01J13/04;B01J13/08;(IPC1-7):B01J13/08;A61K7/00 主分类号 A61J3/07
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