发明名称 Use of Specific Counteranions to Modify the Solubility of Tetrazolium Salts
摘要 This invention relates to sulfonate and phosphonate salts of tetrazolium compounds wherein the anion X.theta.is represented by the formula: (see formula I) wherein R is an organic radical suitable for increasing the solubility of the tetrazolium salt in an aqueous or polar non-aqueous solvent, and the tetrazolium salt is represented by the formula: (see formula II) wherein X.theta. is the anion, R1 and R2 are phenyl groups and R3 is phenyl or 2-thiazolyl wherein the phenyl groups are unsubstituted or substituted as represented by the formula: (see formula III) wherein the Y groups, which can be the same or different, are alkoxy, aryloxy, alkyl, amido, alkylamido; arylamido, alkylthio, arylthio, halo, hydrogen, hydroxy, carbamoyl, carbalkoxy; carboxyl, cyano, nitro, sulfo, sulfonamido; sulfanoyl, trialkylamino or ureido. These salts possess enhanced solubility in various solvents which renders them particularly suitable for use as redox indicators in dry reagent, diagnostic test systems.
申请公布号 CA2084036(A1) 申请公布日期 1993.12.16
申请号 CA19922084036 申请日期 1992.11.27
申请人 MILES INC. 发明人 BLATT, JOEL M.;HATCH, ROBERT P.
分类号 C07C309/04;C07C309/30;C07D257/04;C07D405/04;C07D417/04;C07D417/14;C07F9/11;C07F9/12;C07F9/38;G01N33/52;G01N33/66;(IPC1-7):C07D417/14;C07F9/547;G01N31/22 主分类号 C07C309/04
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