发明名称 Novel taxane derivatives, their preparation and compositions containing same
摘要 Novel taxane derivatives of formula (I), their preparation and pharmaceutical compositions containing same. In general formula (I), Ar is an aryl radical, R1 is a hydrogen atom or an acetyl radical or a radical according to formula (II) (wherein R1 and R2 denote hydrogen, alkyl or together form a heterocycle, n is equal to 2 or 3), R is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl. The novel products of general formula (I) have outstanding tumour prevention activity.
申请公布号 AU4075893(A) 申请公布日期 1993.12.13
申请号 AU19930040758 申请日期 1993.05.18
申请人 RHONE-POULENC RORER S.A. 发明人 JEAN-DOMINIQUE BOURZAT;ALAIN COMMER×ON
分类号 A61K31/335;A61K31/337;A61P35/00;C07D305/14 主分类号 A61K31/335
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