| 发明名称 |
Fluorophenyl amides and their use in therapy |
| 摘要 |
Compounds of formula (I) or pharmaceutically acceptable salts thereof: <CHEM> wherein: Y is C-R1 where R1 is methyl; R2 is hydrogen; R3 and R4 are each methyl; R5 is hydroxy; R6, R8 and R9 are each hydrogen; R7 is 4-fluorophenyl; the R8-N-CO-R7 group being trans to the R5 group; and X is oxygen are useful in the treatment and/or prophylaxis of anxiety and/or mania, and/or depression and/or the effects associated wit withdrawal from substances of above, and/or disorders treatable and/or preventable with anti-convulsive agents. |
| 申请公布号 |
ZA9204267(B) |
申请公布日期 |
1993.12.10 |
| 申请号 |
ZA19920004267 |
申请日期 |
1992.06.11 |
| 申请人 |
SMITHKLINE BEECHAM PLC. |
发明人 |
JOHN MORRIS EVANS;MERVYN THOMPSON;NEIL UPTON |
| 分类号 |
A61K31/35;A61K31/352;A61K31/353;A61K31/435;A61K31/4433;A61K31/47;A61P1/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/30;A61P25/32;A61P25/34;A61P25/36;C07D215/42;C07D215/48;C07D311/68;C07D311/70;C07D311/72;C07D491/04;C07D491/052 |
主分类号 |
A61K31/35 |
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