发明名称 |
AMINO ACID DERIVATIVE AND USE THEREOF |
摘要 |
An amino acid derivative represented by general formula (I), a pharmacologically acceptable salt thereof, and a cancer metastasis inhibitor containing the same, wherein L<1> and L<2> represent each an amino acid residue, etc.; A<1> and A<3> represent each C=O; A<2> represents alkylene, etc.; m and n represent each an integer of 1 to 5; V represents -NHC(=NH)NH2, etc.; W represents -COOH, etc.; R<1> and R<2> represent each hydrogen, alkyl, etc.; R<3> and R<4> represent each hydrogen, etc.; and X and Y represent each -NH- or -O-. The derivative has a potent effect of inhibiting cancer metastasis and is reduced in the activity of inhibiting platelet agglutination and the anticoagulant activity. |
申请公布号 |
WO9324448(A1) |
申请公布日期 |
1993.12.09 |
申请号 |
WO1993JP00734 |
申请日期 |
1993.06.01 |
申请人 |
FUJI PHOTO FILM CO., LTD. |
发明人 |
NISHIKAWA, NAOYUKI;ORIKASA, ATSUSHI;KOMAZAWA, HIROYUKI;KOJIMA, MASAYOSHI;SAIKI, IKUO;AZUMA, ICHIRO |
分类号 |
A61K31/195;A61K31/22;A61K38/00;A61P35/00;A61P43/00;C07C233/47;C07C237/12;C07C279/14;C07C279/20;C07D251/52;C07K5/02;C07K5/06;C07K5/072;(IPC1-7):C07C233/47;C07C237/22 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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