发明名称 AMINO ACID DERIVATIVE AND USE THEREOF
摘要 An amino acid derivative represented by general formula (I), a pharmacologically acceptable salt thereof, and a cancer metastasis inhibitor containing the same, wherein L<1> and L<2> represent each an amino acid residue, etc.; A<1> and A<3> represent each C=O; A<2> represents alkylene, etc.; m and n represent each an integer of 1 to 5; V represents -NHC(=NH)NH2, etc.; W represents -COOH, etc.; R<1> and R<2> represent each hydrogen, alkyl, etc.; R<3> and R<4> represent each hydrogen, etc.; and X and Y represent each -NH- or -O-. The derivative has a potent effect of inhibiting cancer metastasis and is reduced in the activity of inhibiting platelet agglutination and the anticoagulant activity.
申请公布号 WO9324448(A1) 申请公布日期 1993.12.09
申请号 WO1993JP00734 申请日期 1993.06.01
申请人 FUJI PHOTO FILM CO., LTD. 发明人 NISHIKAWA, NAOYUKI;ORIKASA, ATSUSHI;KOMAZAWA, HIROYUKI;KOJIMA, MASAYOSHI;SAIKI, IKUO;AZUMA, ICHIRO
分类号 A61K31/195;A61K31/22;A61K38/00;A61P35/00;A61P43/00;C07C233/47;C07C237/12;C07C279/14;C07C279/20;C07D251/52;C07K5/02;C07K5/06;C07K5/072;(IPC1-7):C07C233/47;C07C237/22 主分类号 A61K31/195
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