发明名称 |
BIPHENYLABKÖMMLINGE, VERFAHREN ZUR HERSTELLUNG UND VERWENDUNG. |
摘要 |
Biphenyl-2,2'-dicarboxylic acid derivs. of formula (I) are new where R1 and R2 are H or methyl. A gallate deriv. of formula (II; X=Y=H; R3 = H, Me, Et or propyl) is halogenated to (II, X=Y= halogen) then dehalogenated (e.g. with zinc) to (II, X= halogen, Y=H). This after methylation and Ullmann condensn. gives cpd. (III, Z=H) which is oxidised with lead tetraacetate, to cpd. (III, Z=COOMe). This on hydrolysis and opt. methylation gives (I). |
申请公布号 |
DE3788043(D1) |
申请公布日期 |
1993.12.09 |
申请号 |
DE19873788043 |
申请日期 |
1987.06.13 |
申请人 |
TSUMURA & CO., TOKIO/TOKYO, JP |
发明人 |
MATSUOKA, YOSHIYUKI, CHUO-KU TOKYO 103, JP;HOSAKA, KUNIO, CHUO-KU TOKYO 103, JP;TAKEDA, SHIGEHUMI, CHUO-KU TOKYO 103, JP;MITSUHASHI, HIROSHI, CHUO-KU TOKYO 103, JP |
分类号 |
C07D317/68;A61K31/357;A61K31/36;A61P1/16 |
主分类号 |
C07D317/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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