发明名称 |
4-Benzylpiperidine derivatives, a process for preparing them and pharmaceutical compositions containing them. |
摘要 |
<p>4-Benzylpiperidine derivatives of the formula: <CHEM> or a pharmaceutically accpetable acid addition salt thereof, wherein X is hydrogen or fluorine and R is hydrogen, or a group selected from p-fluorobenzoyl, alpha-hydroxy-p-fluorobenzyl, p-fluorophenoxy, bis(p-fluorophenyl)methyl and 8-azaspiro [4,5] decane-7,9-dione-8-yl-methyl with the proviso that X and R may not be simultaneously hydrogen and p-fluorobenzoyl respectively. Such compounds are useful as sigma-receptor ligands.</p> |
申请公布号 |
EP0572952(A1) |
申请公布日期 |
1993.12.08 |
申请号 |
EP19930108693 |
申请日期 |
1993.05.28 |
申请人 |
FERRER INTERNACIONAL, S.A. |
发明人 |
FOGUET, RAFAEL;BOLOS, JORDI;SACRISTAN, AURELIO;ORTIZ, JOSE A. |
分类号 |
A61K31/445;A61K31/4427;A61K31/451;A61P9/10;A61P25/18;C07D211/14;C07D211/18;C07D221/20;C07D401/06;(IPC1-7):C07D211/14 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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