摘要 |
PCT No. PCT/US89/00650 Sec. 371 Date Aug. 27, 1990 Sec. 102(e) Date Aug. 27, 1990 PCT Filed Feb. 23, 1989 PCT Pub. No. WO89/08708 PCT Pub. Date Sep. 21, 1989.Provided are ribosome binding sites having an increased number of adenine (A) and thymidine (T) residues as compared to the naturally occurring ribosome binding sites from which they are derived or to which they are related, which allow high level expression of genes encoding heterologous polypeptides, particularly somatotropins, operatively linked thereto.
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