Amino acid derivatives

摘要

The compounds of the formula in which R<1> denotes imidazolylmethyl or pyridylmethyl and A denotes carboxyl, benzyloxycarbonyl, hydroxymethyl or alkylcarbonyloxymethyl, in the form of optically pure diastereomers, diastereomer mixtures, diastereomeric racemates or mixtures of diastereomeric racemates, and pharmaceutically utilisable salts thereof inhibit the action of the natural enzyme renin and can accordingly be used in the form of pharmaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency. They can be prepared by various processes known per se.