| 摘要 |
PURPOSE:To provide a new 6-demethyl-6-formylmitomycin derivative useful as an antitumor agent. CONSTITUTION:The compound of formula I (Y, Z are H, methyl; either of R<1>, R<2> is carbamoyloxymetyl, and the other is H). For example, 6-demethyl-6- formylmitomycin C. The compound of formula I is obtained by reacting a compound of formula II (R is H, 3,4-dimethoxybenzyl) with 2,3-dichloro-5,6- dicyanobenzoquinone. |
