| 摘要 |
Cholinesterase activity is determined by means of the choline obtained by the action of cholinesterase on a compound of the formula: (see formula I) wherein R and R1 can be the same or different, and can be alkyl, such as methyl, ethyl, propyl, butyl, isopropyl, etc.; alkoxy, such as methoxy, ethoxy, propoxy, butoxy, etc.; amino (-NR2R3), wherein R2 and R3 can be the same or different, and can be hydrogen, methyl, ethyl, or propyl, wherein X- is a methyl or an anion, such as halogen (chloro, bromo, or iodo) sulfate, nitrate and acetate; The method of the invention ensures a conveniently low rate of cholinesterase catalyzed hydrolysis and a high degree of accuracy. Certain compounds of formula (I) defined above are novel compounds which are claimed per se.
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