发明名称 Peptide-carbohydrate conjugates generating T-cell immunity
摘要 The present invention relates to a novel class of immunologically active compounds, to processes for their production and to their use in therapy. In particular, the invention provides immunogenic peptide-carbohydrate conjugates useful for generating T cell immunity against tumor-associated carbohydrate structures, or against carbohydrate structures expressed on infectious agents and/or infected host cells. The immunogenic conjugate comprises a peptide component capable of binding a MHC class I molecule and a carbohydrate component having the same immunogenic characteristics of the carbohydrate structure on the tumor cell, infectious agent or the infected cells.
申请公布号 AU4274693(A) 申请公布日期 1993.11.29
申请号 AU19930042746 申请日期 1993.04.23
申请人 AKTIEBOLAGET ASTRA 发明人 MIKAEL JONDAL
分类号 A61K38/00;A61K31/00;A61K39/00;A61K39/385;A61P35/00;C07H15/04;C07H15/18;C07K1/113;C07K9/00;C07K14/005;C07K14/11;C08B 主分类号 A61K38/00
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