摘要 |
Novel taxane derivatives of formula (I), their preparation and pharmaceutical compositions containing same. In general formula (I), Ar is an aryl radical, R1 is a hydrogen atom or an acetyl radical or a radical according to formula (II) (wherein R1 and R2 denote hydrogen, alkyl or together form a heterocycle, n is equal to 2 or 3), R is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl. The novel products of general formula (I) have outstanding tumour prevention activity.
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