发明名称 Nouveaux dérivés du taxane, leur préparation et les compositions qui les contiennent.
摘要 Novel taxane derivatives of formula (I), their preparation and pharmaceutical compositions containing same. In general formula (I), Ar is an aryl radical, R1 is a hydrogen atom or an acetyl radical or a radical according to formula (II) (wherein R1 and R2 denote hydrogen, alkyl or together form a heterocycle, n is equal to 2 or 3), R is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl. The novel products of general formula (I) have outstanding tumour prevention activity.
申请公布号 FR2691460(A1) 申请公布日期 1993.11.26
申请号 FR19920006177 申请日期 1992.05.21
申请人 RHONE POULENC RORER SA 发明人 BOURZAT JEAN-DOMINIQUE;COMMERCON ALAIN
分类号 A61K31/335;A61K31/337;A61P35/00;C07D305/14;(IPC1-7):C07D305/14 主分类号 A61K31/335
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