发明名称 IMPROVED METHODS FOR THE PREPARATION OF ENDOTOXIN-BINDING PROTEINS
摘要 Disclosed are improvements in methods for the isolation of endotoxin-binding proteins which are secreted by transfected host cells in appropriate cell culture media. In its preferred embodiment, the invention comprises addition of a cation exchange material to the media as the means of increasing the yield of recombinant endotoxin-binding proteins, such as bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein.
申请公布号 WO9323540(A2) 申请公布日期 1993.11.25
申请号 WO1993US04752 申请日期 1993.05.19
申请人 XOMA CORPORATION 发明人 GRINNA, LYNN, S.
分类号 C12N15/09;C07K1/18;C07K14/47;C07K19/00;C12N5/00;C12N15/00;C12N15/12;C12N15/62;C12P21/00;C12P21/02;C12R1/91 主分类号 C12N15/09
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