Compounds of formula (I), wherein X is sulfur or oxygen are inhibitors of the 5 alpha -reductase enzyme and isozymes thereof. The compounds are useful for the treatment of hyperandrogenic disease conditions and diseases of the skin and scalp.
申请公布号
WO9323041(A1)
申请公布日期
1993.11.25
申请号
WO1993US04771
申请日期
1993.05.19
申请人
MERCK & CO., INC.
发明人
WITZEL, BRUCE, E.;RASMUSSON, GARY, H.;TOLMAN, RICHARD, L.;YANG, SHU, SHU