FUSED IMIDAZOLE AND TRIAZOLE DERIVATIVES AS 5-HT1 RECEPTOR AGONISTS

摘要

Compounds of formula (I) wherein Q represents the residue of a six-membered aromatic or heteroaromatic nucleus containing zero, one or two nitrogen atoms; V represents nitrogen or C-A2; E represents a bond or a straight or branched alkylene chain containing from 1 to 4 carbon atoms; F represents a group of formula (a); U represents nitrogen or C-R2; B represents oxygen, sulphur or N-R3; R1 represents -CH¿2?.CHR?4.NR6R7¿ or a group of formula (i), (ii), (iii) or (iv); are selective agonists of 5-HT¿1?-like receptors and are therefore useful in the treatment of clinical conditions, in particular migraine and associated disorders, for which a selective agonist of these receptors is indicated.