发明名称 |
BPI-IMMUNOGLOBULIN FUSION PROTEINS |
摘要 |
Disclosed are novel hybrid fusion proteins comprising at their amino terminus, bactericidal/permeability-increasing protein or a biologically active fragment thereof and, at their carboxy terminus, at least one immunoglobulin heavy chain constant domain useful in treating bacterial infection. Also disclosed are DNA sequences encoding such proteins, recombinant methods for production of the proteins, and pharmaceutical preparations containing the recombinant products. |
申请公布号 |
WO9323434(A2) |
申请公布日期 |
1993.11.25 |
申请号 |
WO1993US04754 |
申请日期 |
1993.05.19 |
申请人 |
XOMA CORPORATION |
发明人 |
THEOFAN, GEORGIA;GRINNA, LYNN, S.;HORWITZ, ARNOLD |
分类号 |
A61K38/00;C07K14/47;C07K19/00;C12N1/21;C12N15/12;C12N15/13;C12N15/63;C12N15/85;C12P21/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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