| 发明名称 |
A NOVEL RECEPTOR FOR alpha 4 INTEGRINS AND METHODS BASED THEREON |
| 摘要 |
The present invention is directed to a novel receptor for alpha 4 integrins such as VLA-4, that is distinct from VCAM-1 and from fibronectin. Isolated nucleic acids encoding the receptor and antibodies to the receptor are also provided. The invention is also directed to pharmaceutical compositions, and methods of treating disorders involving an undesirable inflammatory or immune response by administering the VLA-4 receptor of the invention. |
| 申请公布号 |
WO9323526(A1) |
申请公布日期 |
1993.11.25 |
| 申请号 |
WO1993US04956 |
申请日期 |
1993.05.21 |
| 申请人 |
CENTER FOR BLOOD RESEARCH, INC. |
发明人 |
VONDERHEIDE, ROBERT, H.;SPRINGER, TIMOTHY, A. |
| 分类号 |
A61K38/00;C07K14/705;C07K16/28;C12N1/21;G01N33/569;G01N33/68;(IPC1-7):C12N1/21;C12N15/00;C07K13/00;C07K15/28;G01N33/53 |
主分类号 |
A61K38/00 |
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