ENZYMATIC PROCESS FOR PRODUCTION OF S-6-METHOXY- alpha -METHYL-2-NAPHTHALENEACETIC ACID
摘要
The enantioselective hydrolysis of racemic naproxen esters by ester hydrolases using hydrolases derived from a panel of microorganisms is described, the most suitable of which was the microorganism Zopfiella latipes. The ester hydrolases are of use in a low cost, high yield hydrolysis of racemic naproxen esters.
申请公布号
WO9323547(A1)
申请公布日期
1993.11.25
申请号
WO1993US04392
申请日期
1993.05.14
申请人
SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED;CHAN, HARDY, W.