| 发明名称 |
HEPATOCYTE GROWTH FACTOR VARIANTS |
| 摘要 |
2118012 9323541 PCTABS00028 The invention concerns hepatocyte growth factor (HGF) amino acid sequence variants. The preferred variants are resistant to proteolytic cleavage by enzymes capable of in vivo conversion of HGF into its two-chain form and/or contain a mutation within the protease domain of HGF.
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| 申请公布号 |
CA2118012(A1) |
申请公布日期 |
1993.11.25 |
| 申请号 |
CA19932118012 |
申请日期 |
1993.05.17 |
| 申请人 |
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发明人 |
GODOWSKI, PAUL J.;LOKKER, NATHALIE A.;MARK, MELANIE R. |
| 分类号 |
C12N15/09;A61K38/00;A61K38/22;A61K38/27;A61K47/48;A61P43/00;C07H21/04;C07K14/475;C07K14/52;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/10;C12N15/19;C12P21/02;C12R1/91;(IPC1-7):C12N15/18;A61K38/18;A61K38/48;C12N15/57;C12N9/64 |
主分类号 |
C12N15/09 |
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