摘要 |
PURPOSE:To produce a perfluoroalkyl-substituted benzene derivative useful as a compounding component of a liquid crystal composition for display element, etc., by using a simple process compared with conventional process and to enable the production of a long-chain derivative which is difficult to be produced by conventional process. CONSTITUTION:A perfluoroalkylbenzene derivative of formula II can easily be produced by reacting a benzene derivative of formula I (X is I or Br; R is H, alkyl, cycloalkyl or aralkyl) with a perfluoroalkane of the formula CmH2m+1 Y (Y is I or Br; m is integer of 1-18) in the presence of a copper catalyst. The process enables the production of a long-chain perfluoroalkyl-substituted benzene derivative which is difficult to produce by conventional process. The above reaction can be carried out at <=200 deg.C or thereabout, preferably at 100-140 deg.C in a polar solvent such as N-methylpyrrolidone, dimethyl sulfoxide or HMPA. The copper catalyst may be Raney copper, Ulmann copper or Urushibara copper, however, copper powder for conventional reaction use may be used as it is as the catalyst. |