发明名称
摘要 New hapalindole-type alkaloids called A89271 A-F and I are antifungal and antitumor agents. Methods for preparing them and for preparing hapalindoles G and H by culturing the blue-green alga Fischerella ambigua ATCC 55210 are provided. Methods for preparing A89271 factors B and F by culturing the blue-green alga Hapalosiphon hibernicus ATCC 55225 and a biologically pure culture of this alga are also provided. Further provided are methods and compositions for the inhibition of fungal growth and the treatment of susceptible neoplasms.
申请公布号 JPH05306271(A) 申请公布日期 1993.11.19
申请号 JP19920289958 申请日期 1992.10.28
申请人 ELI LILLY & CO;UNIV HAWAI 发明人 ROZANNU BONJIYOUKURIAN;RICHIYAADO ERIOTSUTO MUUA;GUREGORII MASHIYUU REON PATAASON;TEIMU AREN SUMITOKA
分类号 A61K31/40;A01N43/38;A01N43/90;A61K31/403;A61P31/04;A61P35/00;C07D209/56;C07D209/70;C07D209/80;C07D491/06;C07D491/08;C12N1/12;C12P17/08;C12P17/10;C12P17/18;C12R1/89;(IPC1-7):C07D209/56 主分类号 A61K31/40
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