发明名称 |
Wild-type measles virus glycoproteins: vaccine and detection method therefor |
摘要 |
The present invention provides nucleic acids encoding consensus hemagglutinin and consensus fusion polypeptides which contain at least one amino acid substitution relative to the Moraten vaccine strain that is found in at least one strain of wild-type measles virus. Nucleic acid reagents useful for detecting and differentiating wild-type measles strains by polymerase chain reaction and a method utilizing the same are provided. Recombinant vectors comprising nucleic acids encoding the consensus hemagglutinin and/or the consensus fusion polypeptides are also provided. |
申请公布号 |
AU4047093(A) |
申请公布日期 |
1993.11.18 |
申请号 |
AU19930040470 |
申请日期 |
1993.04.08 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DE |
发明人 |
JENNIFER S ROTA;WILLIAM J BELLINI |
分类号 |
G01N33/569;A61K39/00;A61K39/165;A61P31/12;C07K14/12;C07K16/00;C07K19/00;C12N15/09;C12N15/45;C12P21/02;C12P21/08;C12Q1/68;C12R1/92 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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