PERHYDROAZACYCLOALKA (1,2-A) IMIDAZOLE DERIVATIVES AND USE THEREOF AS NOOTROPIC AGENTS

摘要

NEW PERHYDROAZACYCLOALKA¢1,2-A!IMIDAZOLE DERIVATIVES AND USE THEREOF AS NOOTROPIC AGENTS Compounds of structure (1) <IMG> (I) in which, R1 is hydrogen, C1-4alkyl, CHR6CONHR7 or CHR6COOR7 in which R6 and R7 are each hydrogen or C1-4alkyl; R2 is hydrogen, C1-5alkyl or any residue R2 of an amino acid R2CH(NH2)COOH; R3 is hydrogen, C1-4alkyl, CONH2 or CO2R8 in which R8 is hydrogen or C1-4alkyl; and n is 2, 3 or 4 processes for their preparation, intermediates useful in their preparation, pharmaceutical formulations containing them and their use in therapy as nootropic agents.