发明名称 |
IMPROVED SOLUBILIZATION AND STABILIZATION OF FACTOR VIII COMPLEX |
摘要 |
A process for facilitating the reconstitution of lyophilized Factor VIII complex compositions, and compositions of Factor VIII complex, which are readily reconstituted. The process of the present invention comprises providing a purified Factor VIII complex preparations; adding a stabilization agent comprising arginine; lyophilizing the stabilization agent-Factor VIII complex solutions; and reconstituting the lyophilized stabilization agent-Factor VIII complex by contacting it with solvent for less than one minute. |
申请公布号 |
WO9322336(A1) |
申请公布日期 |
1993.11.11 |
申请号 |
WO1993US04045 |
申请日期 |
1993.04.29 |
申请人 |
ALPHA THERAPEUTIC CORPORATION |
发明人 |
BHATTACHARYA, PRABIR;MOTOKUBOTA, TOSHIHARU |
分类号 |
A61K38/37;C07K14/755;(IPC1-7):C07K3/20;A61K37/02;A61K35/16;C07K3/28 |
主分类号 |
A61K38/37 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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