| 摘要 |
<p>Oral pharmaceutical medications and methods are disclosed for providing immediate and sustained relief from pain, discomfort and/or symptoms associated with episodic heartburn. The oral medications consist essentially of antacids and histamine H2-receptor antagonists, and may be administered on an as-needed basis in liquid or solid dosage forms. Antacids, such as sodium bicarbonate, calcium carbonate, magnesium hydroxide, aluminum hydroxide and high potency flavored antacids, may be used in combination with the histamine H2-receptor antagonist. Histamine H2-receptor antagonists which may be used in combination include, for example, cimetidine, ranitidine, famotidine and nizatidine. In carrying out the methods, an antacid and histamine H2-receptor antagonist may be orally administered together as a single unitary dose in the form of a liquid or solid, or orally administered substantially together, but separately as either liquids or solids or a combination thereof. The oral medications when formulated as a single unitary dose may include other additives, such as, for example, antiflatulents, flavorings, sweeteners and the like.</p> |
