发明名称 |
RAPID DETECTION OF ANTIBIOTIC RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS |
摘要 |
Multidrug resistant strains of Mycobacterium tuberculosis represent a considerable threat to public health worldwide. Resistance to isoniazid (INH), rifampicin or analogues thereof, or streptomycin, i.e. key components of anti-tuberculosis regimens, need frequently to be detected. The invention involves the detection of a mutation in either the katG gene (isoniazid resistance), the rpoB gene (rifampicin resistance) or rpsL gene (streptomycin resistance). |
申请公布号 |
WO9322454(A1) |
申请公布日期 |
1993.11.11 |
申请号 |
WO1993EP01063 |
申请日期 |
1993.04.30 |
申请人 |
INSTITUT PASTEUR;MEDICAL RESEARCH COUNCIL;ASSISTANCE PUBLIQUE;UNIVERSITE PIERRE ET MARIE CURIE;UNIVERSITE DE BERNE |
发明人 |
HEYM, BEATE;COLE, STEWART;YOUNG, DOUGLAS;ZHANG, YING;HONORE, NADINE;TELENTI, AMALIO;BODMER, THOMAS |
分类号 |
C12N15/09;C12N9/08;C12Q1/18;C12Q1/68;C12R1/32;G01N33/15;G01N33/50 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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