发明名称 |
CDNA SEQUENCE OF DENGUE VIRUS SEROTYPE 1 (SINGAPORE STRAIN) |
摘要 |
DEN1-S275/90 (ECACC V92042111) is a new strain of Dengue virus serotype 1. The complete cDNA sequence of this virus has been cloned and protein-coding fragments thereof have been used in the construction of expression plasmids. DEN1-S275/90 in inactivated form, DEN1-S275/90 polypeptides or fusion proteins thereof can be incorporated into vaccines for immunisation against DEN1-S275/90 and other DEN1 viruses. The invention further provides diagnostic reagents e.g. labelled antibodies to DEN1-S275/90 proteins, and kits to detect DEN1 virus. |
申请公布号 |
WO9322440(A1) |
申请公布日期 |
1993.11.11 |
申请号 |
WO1993CA00182 |
申请日期 |
1993.04.28 |
申请人 |
NATIONAL UNIVERSITY OF SINGAPORE;TAN, YIN-HWEE |
发明人 |
TAN, YIN-HWEE;FU, JIANLIN;TAN, BOON-HUAN;YAP, EU-HIAN;CHAN, YOW-CHEONG |
分类号 |
A61K39/00;C07K14/18;C12N7/00;C12N15/40;(IPC1-7):C12N15/40;C07K13/00;C12N15/62;A61K39/12;C12P21/00;G01N33/50 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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