| 摘要 |
The invention provides means for denaturing or eliminating factors interfering biochemical reactions by simple treatment without requiring separation of any denatured product precipitate, to thereby make it possible to assay, in particular, beta -glucan and endotoxin in blood-derived samples rapidly and efficiently with high sensitivity. Thus, a pretreating reagent system comprising a hexadimethrine compound and an alkali metal hydroxide, a pretreating reagent system for beta -glucan assay comprising an alkali metal hydroxide as a main component, a pretreatment method which uses either of the pretreating reagent systems, a method of assaying a substance specifically reacting with a Limulus reagent utilizing the Limulus reaction which uses the pretreatment method, an assay kit comprising at least the pretreating reagent system and a Limulus reagent, and a method of diagnosing infectious diseases based on the results obtained by the above assay method are provided. <IMAGE> |
