| 摘要 |
<p>The invention relates to a polypeptide comprising a peptide sequence belonging to the sequence of the first 62 amino acids of the terminal portion of the CORE protein (or capsid) of the human hepatitis C virus (HCV), the said polypeptide comprising either an isolated peptide sequence which is composed of the 45 N-terminal amino acids of the said protein, 1 to 10 amino acids being optionally amputated from its N-terminal portion and/or its C-terminal portion, or an immunogenic sequence equivalent to the said peptide sequence, and exhibiting immunological cross-reactivity with the said peptide sequence, with respect to HCV. The invention also relates to a polypeptide composition, a reagent and a means of detecting the HCV virus, a process and a device for detecting anti-HCV antibodies, an immunotherapeutic composition and antibodies directed against HCV.</p> |
