发明名称 |
Methods for detection of human gamma, gamma T cell receptor |
摘要 |
The present invention provides purified polypeptides which comprise at least a portion of a delta T cell receptor polypeptide, a gamma T cell receptor polypeptide, a gamma , gamma T cell receptor complex or a gamma , delta T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.
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申请公布号 |
US5260223(A) |
申请公布日期 |
1993.11.09 |
申请号 |
US19880187698 |
申请日期 |
1988.04.29 |
申请人 |
PRESIDENT & FELLOWS OF HARVARD COLLEGE;DANA FARBER CANCER INSTITUTE & T CELL DIAGNOSTICS, INC.;HARVARD COLLEGE |
发明人 |
BRENNER, MICHAEL B.;STROMINGER, JACK L.;SEIDMAN, JOHN G.;IP, STEPHEN H.;KRANGEL, MICHAEL S. |
分类号 |
G01N33/53;A61K39/395;C07K14/725;C07K16/28;C12N5/10;C12N15/02;C12N15/09;C12P21/00;C12P21/02;C12P21/08;C12R1/91;G01N33/569;G01N33/577;(IPC1-7):G01N33/566 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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