Purified DNA of the 170-kd surface Gal/GalNAc adherence lectin of pathogenic E. histolytica +B

摘要

cDNA encoding the 170 kd subunit of Gal/GalNAc lectin in various strains of E. histolytica is provided. Availability of this cDNA permits the use of diagnostic assays to distinguish pathogenic from nonpathogenic strains based on DNA hybridization, and further permits antisense approaches to interrupting the production of this lectin.