发明名称 |
METHOD FOR THE PREPARATION AND PURIFICATION OF PHOSPHOLIPID MIXTURES FREE FROM CONTAMINATION BY UNCONVENTIONAL VIRUSES |
摘要 |
A phospholipid mixture in which the biological and pharmacological properties are maintained but from which unconventional viruses causing e.g. bovine spongiform encephalopathy are selectively eliminated may be prepared by extraction of phospholipids from bovine brain by a mixture of organic solvents of which one is a chlorinated hydrocarbon or by silica gel chromatography with elution with a succession of eluents consisting of chloroform, lower alcohols and water, or by a combination of extraction and silica gel chromatography. Purified phospholipids can be used in pharmaceutical compositions. |
申请公布号 |
WO9321190(A1) |
申请公布日期 |
1993.10.28 |
申请号 |
WO1993EP00915 |
申请日期 |
1993.04.16 |
申请人 |
FIDIA S.P.A. |
发明人 |
DI MARTINO, ALESSANDRO;CALLEGARO, LANFRANCO;TOFFANO, GINO |
分类号 |
A61K35/30;C07F9/10;(IPC1-7):C07F9/10;A61K31/685 |
主分类号 |
A61K35/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|