摘要 |
<p>The present invention relates to nucleic acid sequences encoding amino acid sequences of the α, β, and η subunits of the high affinity receptor for immunoglobulin E, and for amino acid sequences of the subunits. The invention further relates to a method of producing the receptor by expressing cDNA for its α, β, and η subunits in a host cell simultaneously. Aspects of the invention are methods and compositions to produce the human beta subunit, as well as to inhibit its function, thereby treating or preventing allergic reactions.</p> |