Process for the preparation of 2-oxytetrahydrofurans.

摘要

A two-phase process for preparing 2-oxytetrahydrofurans is disclosed. Aqueous 4-hydroxybutanal, which is readily available from a commercial hydroformylation process, is combined with an organic solution of a hydroxy compound in the presence of an acid catalyst to produce a 2-oxytetrahydrofuran. 2-Oxytetrahydrofurans are useful intermediates for pharmaceuticals or for the synthesis of 2,3-dihydrofuran.