发明名称 |
Anti-HIV agent |
摘要 |
The invention relates to an anti-HIV agent comprising as an effective component a plasma protein of which the polarity of the amino group of the amino acid residue constituting the plasma protein is chemically modified into a negative moiety by a carboxylic acid, for example, by maleic anhydride or succinic anhydride. Plasma proteins modified with dicarboxylic anhydride, which are the effective components of the anti-HIV agent of this invention, inhibit the formation of large cells in mixed culturing of HIV infected cells and non-infected cells as well as the direct infection of helper T cells with HIV. They are very safe compounds and are expected to be applicable to the treatment of HIV infected patients
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申请公布号 |
US5256412(A) |
申请公布日期 |
1993.10.26 |
申请号 |
US19920930349 |
申请日期 |
1992.08.17 |
申请人 |
MEIJI MILK PRODUCTS CO., LTD. |
发明人 |
TSUNOO, HAJIME;TAKAMI, MASAO;MIZUMOTO, KENJI |
分类号 |
A61K38/36;A61K38/38;A61K38/40;C07K16/00;(IPC1-7):A61K37/02 |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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