| 摘要 |
PURPOSE:To obtain the bioimplantation material which is used by being packed into the defective part of the bone in oral surgery, orthopedics, etc., and with which the neogenetic bone is liable to grow by forming the films of uncrosslinked gelatin on the surfaces of composites in which the gelatin of a crosslinked state carries the particles of a calcium phosphate compd. CONSTITUTION:This bioimplantation material is produced in a granular shape by subjecting the particles 2 consisting of the calcium phosphate compd. to vacuum heat drying, etc., to form the composites 4 in which the gelatin 3 of the crosslinked state carries the particles, further, forming the films 5 consisting of the uncrosslinked gelatin on the surfaces of such composites 4 and aggregating these composites. The films Z consisting of the uncrosslinked gelatin are soluble in water and, therefore, have an adequate viscosity when kneading with liquid, such as physiological salt soln. Further, the composites 4 carrying the particles 2 of the calcium phosphate compound become insoluble in water by crosslinking of the gelatin and, therfore, even if this material is packed into the defective part of the bone, the material does not move and the bone is regenerated and grows in an early period of time. |
