发明名称 Substituted 2-aminotetralins and pharmaceutical use
摘要 Certain novel compounds having the structural formula <IMAGE> where R2, R3 and R4 are each selected from the group consisting of H and OA; A is H or is selected from the group consisting of hydrocarbyl radicals, e.g. lower alkyl radicals, i.e. methyl, ethyl, propyl, etc., or <IMAGE> wherein R5 is selected from the group consisting of hydrocarbyl radicals, e.g. alkyl and aromatic residues; n is 2 or 3; and R1 is selected from the group consisting of organic radicals having fused aromatic rings, that is, radicals comprising at least two rings that share a pair of carbon atoms or share a carbon and nitrogen atom are useful for inducing a dopaminergic response and reducing the intraocular pressure in a mammal.
申请公布号 US5256661(A) 申请公布日期 1993.10.26
申请号 US19920951993 申请日期 1992.09.28
申请人 WHITBY RESEARCH, INC. 发明人 HORN, ALAN S.
分类号 A61K31/135;A61K31/22;A61K31/235;A61K31/275;A61K31/34;A61K31/38;A61K31/40;A61K31/415;A61K31/44;C07D209/08;C07D333/20;C07D333/28;C07D333/58;(IPC1-7):A61K43/08;A61K43/10;A61K43/38;A61K43/42 主分类号 A61K31/135
代理机构 代理人
主权项
地址