发明名称 2,4-DIOXOIMIDAZOLIDINE DERIVATIVES
摘要 23233-274 The present invention relates to 2,4-dioxoimidazolidine derivatives of the general formula I (I) wherein R1 is, for example,-(CH2)n-NH-X, where n is an integer from 1 to 6 and X is, for example, hydrogen or (C1-C6)-alkyl, R2 is hydrogen or (C1-C6)-alkyl, R3 is hydrogen or phenyl, R4 is, for example, COOR5, where R5 is (C1-C28)-alkyl and Y is, for example, -(CH2)m-CO- radical where m represents an integer from 1 to 4. The compounds of the invention are useful as inhibitors of platelet aggregation, metastasis of carcinoma cells and osteoclast binding to the bone surfaces.
申请公布号 CA2094773(A1) 申请公布日期 1993.10.25
申请号 CA19932094773 申请日期 1993.04.23
申请人 CASSELLA AKTIENGESELLSCHAFT 发明人 ZOLLER, GERHARD;KOENIG, WOLFGANG;KNOLLE, JOCHEN;JUST, MELITTA;JABLONKA, BERND
分类号 A61K31/415;A61K31/4166;A61K31/42;A61K31/425;A61K38/00;A61K38/04;A61P7/02;A61P19/10;A61P35/00;A61P43/00;C07D233/72;C07D233/76;C07D233/80;C07D233/96;C07D403/12;C07K5/08;C07K5/10;C07K5/117;(IPC1-7):C07K5/02 主分类号 A61K31/415
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