发明名称 |
POLYAZAMACROCYCLIC COMPOUNDS AND THEIR COMPLEXES WITH METAL IONS |
摘要 |
A nuclear magnetic resonance contrast composition which comprises a tetraazamacrocyclic compound - paramagnetic lanthanide complex having the formula: <CHEM> where x is 2, 3 or a combination of p 2(s) and q 3(s) where p + q = 4; R is (CH2)zP(=O)OR<1>OR<2>; R<1> is H or CH3; R<2> is CnH1+2n; z is 1 to 3; r is 2 or 3; M is a paramagnetic lanthanide; and n is 4 to 6. The nuclear magnetic resonance contrast compositions are particularly suitable for liver imaging in a subject. |
申请公布号 |
IL106164(D0) |
申请公布日期 |
1993.10.20 |
申请号 |
IL19930106164 |
申请日期 |
1993.06.29 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;THE DOW CHEMICAL COMPANY |
发明人 |
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分类号 |
A61K49/00;A61K49/04;A61K49/06;A61K51/00;A61K51/04;C07D255/02;C07D257/02;C07D259/00;C07F;C07F9/6515;C07F9/6524;C08G59/70;(IPC1-7):C07F/ |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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