发明名称 Production of recombinant proteins using herpes virus promoters and VP16 transactivators.
摘要 <p>Stable cell lines are produced to express high levels of a gene product of interest using VP16, a herpes simplex virus transactivator, and a promoter from herpes simplex virus which is a target for VP16. The transactivator and promoter are introduced to a cell line separately using antibiotic resistance genes as selectable markers on separate vectors.</p>
申请公布号 EP0566554(A2) 申请公布日期 1993.10.20
申请号 EP19930870043 申请日期 1993.03.12
申请人 MONSANTO COMPANY 发明人 HIGHKIN, MAUREEN KATHERINE;HIPPENMEYER, PAUL JEROME
分类号 C12N5/10;C07K14/52;C07K14/61;C07K14/705;C12N9/10;C12N9/72;C12N15/09;C12N15/869;C12P21/02;C12R1/91;G01N33/50;(IPC1-7):C12N15/85;C12N7/02;C12Q1/18 主分类号 C12N5/10
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