发明名称 |
FOERBAETTRADE RETARDSYSTEM FOER FOERDROEJD FRIGOERING AV MEDICINSKT OCH/ELLER BIOLOGISKT VERKANDE AEMNEN FRAON DEPOTBAERARMATERIAL |
摘要 |
<p>PCT No. PCT/EP92/00825 Sec. 371 Date Oct. 18, 1993 Sec. 102(e) Date Oct. 18, 1993 PCT Filed Apr. 11, 1992 PCT Pub. No. WO92/18108 PCT Pub. Date Oct. 29, 1992The invention relates to the use of free radical-reactive cross-linker components based on olefinically unsaturated esters of lower hydroxycarboxylic acids and/or oligomers thereof for modifying depot materials, and especially retard systems, which contain medicinal and/or biological valuable materials in admixture with a carrier material in a sustained release form. The cross-linkers are present as polymer compounds in the application form of the retard system and may be provided in the retard system or depot material to be applied in a largely homogeneous as well as in a non-uniform distribution. The invention also relates to retard systems which contain medicinal and/or biological valuable materials and have been based on oligomer and/or polymer compounds of lower hydroxycarboxylic acids as carrier materials providing a sustained release of the active substance. The retard systems and/or depot materials are modified with polymer compounds prepared from olefinically unsaturated esters of lower hydroxycarboxylic acids and/or oligomers thereof.</p> |
申请公布号 |
FI934569(A0) |
申请公布日期 |
1993.10.15 |
申请号 |
FI19930004569 |
申请日期 |
1993.10.15 |
申请人 |
HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN |
发明人 |
RITTER, WOLFGANG;LEHMANN, RUDOLF;SORG, RAINER |
分类号 |
A61K9/00;A61K;A61K9/20;A61K9/22;A61K47/30;A61K47/32;A61K47/34;A61L26/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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