| 摘要 |
<p>Myc-induced cell death is inhibited in cultured cells, for example hybridoma cells, by expressing bc12. Myc-induced cell death is de-inhibited in tumour cells by administering bc12 antisense oligonucleotides. Compounds which modulate apoptosis may be detected in an assay using a proto-oncogene such as Myc.</p> |
