发明名称 Compsn. for treating multiple sclerosis - comprising protein, peptide or aminoacid with low glycine, glutamine, glutamic acid, arginine and phenylalanine content
摘要 Compsn. for treatment of multiple sclerosis (MS) by intravenous or oral admin. in association with a diet in which the nutritional protein supply is zero in acute cases, of no more than 0.5 g/kg (body wt.) in chronic cases, comprises a protein, protein mixt., protein hydrolysate, peptide, peptide mixt. or aminoacid mixt., opt. together with substances not contg. aminoacids. The compsn. has a total glycine, glutamine and glutamic acid content of no more tha 15 wt.%, an arginine content of no more than 1 wt.% and a phenylalanine content of no more than 3.5 wt.% and/or contains these aminoacids in a chemically modified form that cannot be transaminated in vivo. The compsn. is administered in a daily dose of up to 2 g/kg. ADVANTAGE - The compsn. reduces the symptoms of MS and retards the progress of the disease
申请公布号 DE4211878(A1) 申请公布日期 1993.10.14
申请号 DE19924211878 申请日期 1992.04.09
申请人 KLUGE, RALF, DR.MED., O-4020 HALLE, DE;WASICKI, PETER, DR.RER.NAT., O-1055 BERLIN, DE 发明人 KLUGE, RALF, DR.MED., O-4020 HALLE, DE;WASICKI, PETER, DR.RER.NAT., O-1055 BERLIN, DE
分类号 A61K31/195;A61K38/01;(IPC1-7):A61K37/02 主分类号 A61K31/195
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